13 June 2011

Lacidipine Type Calcium Channel Blocker Drug

     ,  3 comments
Description:
Lacidipine is a group of type calcium channel blocker drug. Lacidipine works by relaxing the heart muscle and blood vessels.

Indications:
To treat high blood pressure (hypertension).

Dosage:

  • The initial dose: 2 mg by mouth (orally), 1 times daily

  • May be increased to 4 mg, if necessary to 6 mg by mouth (orally), 1 time a day after at least 3-4 weeks away.

Side Effects:

  • CV effects (decreased cardiac function, hypotension, heart failure is getting worse, edema, skin redness, bradycardia), GI effects (constipation); CNS effects (headache, dizziness).

  • HR regulate calcium antagonists (Diltiazem, Gallopamil & verapamil); AV dissociation, AV block, bradycardia, and sinus stem dysfunction.

  • Short-acting dihydropyridine agents should be avoided because it has the potential to increase the risk of adverse cardiac events.

Special Instructions:

  • Contraindicated in patients who clearly have decompensated HR, although vasoselective dihydropyridine (eg Amlodipine and Felodipine) can be accepted by patients with reduced LV solution.

  • HR which regulates calcium antagonists contraindicated in patients with bradycardia, sinus stem dysfunction, and AV nodal block.

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3 comments:

  1. eco lawn grass seed15 July 2011 at 22:30

    My mom had a mild stroke. her CKMB is 246 (normal range is approx. 2-6 only).. her CK total and CK MM was normal, still she experiencing unstable angina. Nitroglycerine is effective but the pain is still intermittent. she had Omeprazole, Lacidipine, Atorvastatin and Clopidogrel as her maintainance medication.

    ReplyDelete
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