Description:
Tramadol is a powerful analgesic that works on opiate receptors.
Tramadol stereospecific binding to receptors in the central nervous system and blocks pain sensation and response to pain. Besides that tramadol inhibits the release of neurotransmitters from afferent nerves are sensitive to stimuli, pain impulses consequently hampered.
Composition:
Each ml of injection contains 50 mg of tramadol hydrochloride.
Indications:
Effective for the treatment of acute and chronic pain are severe, including post-surgical pain, pain caused by diagnostic measures.
Dosage:
Oral therapy
Adults and children over 14 years.
Typical dosage:
single dose of 50 mg. The dose is usually sufficient to relieve pain, if it still feels the pain can be added to 50 mg after an interval of 30-60 minutes.
Maximum dose:
400 mg a day.
Doses are very dependent on the intensity of pain suffered.
Patients with impaired liver and kidney with creatinine clearance <30 ml / min:
50-100 mg every 12 hours, maximum 200 mg a day.
Parenteral Therapy
The dose administered should be adjusted to the intensity of pain. If no other instructions from the doctor, the dose given is as follows:
Adults or children over 14 years:
iv: 100 mg (1 ampule), slowly injected or dissolved in the infusion solution, and then infused.
i.m.: 100 mg (1 ampule)
subcutaneous: 100 mg (1 ampule)
The dose is usually sufficient to relieve pain. If you still feel pain, you can add 1 capsule tramadol 50 mg or 50 mg of tramadol injection (1 ml) after an interval of 30-60 minutes. In patients with impaired liver or renal function, dosage adjustments need to be done. The maximum dose of 400 mg / day.
Tramadol is a powerful analgesic that works on opiate receptors.
Tramadol stereospecific binding to receptors in the central nervous system and blocks pain sensation and response to pain. Besides that tramadol inhibits the release of neurotransmitters from afferent nerves are sensitive to stimuli, pain impulses consequently hampered.
Composition:
Each ml of injection contains 50 mg of tramadol hydrochloride.
Indications:
Effective for the treatment of acute and chronic pain are severe, including post-surgical pain, pain caused by diagnostic measures.
Dosage:
Oral therapy
Adults and children over 14 years.
Typical dosage:
single dose of 50 mg. The dose is usually sufficient to relieve pain, if it still feels the pain can be added to 50 mg after an interval of 30-60 minutes.
Maximum dose:
400 mg a day.
Doses are very dependent on the intensity of pain suffered.
Patients with impaired liver and kidney with creatinine clearance <30 ml / min:
50-100 mg every 12 hours, maximum 200 mg a day.
Parenteral Therapy
The dose administered should be adjusted to the intensity of pain. If no other instructions from the doctor, the dose given is as follows:
Adults or children over 14 years:
iv: 100 mg (1 ampule), slowly injected or dissolved in the infusion solution, and then infused.
i.m.: 100 mg (1 ampule)
subcutaneous: 100 mg (1 ampule)
The dose is usually sufficient to relieve pain. If you still feel pain, you can add 1 capsule tramadol 50 mg or 50 mg of tramadol injection (1 ml) after an interval of 30-60 minutes. In patients with impaired liver or renal function, dosage adjustments need to be done. The maximum dose of 400 mg / day.
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