Tramadol 50 mg / ml

Description:
Tramadol is a powerful analgesic that works on opiate receptors.
Tramadol stereospecific binding to receptors in the central nervous system and blocks pain sensation and response to pain. Besides that tramadol inhibits the release of neurotransmitters from afferent nerves are sensitive to stimuli, pain impulses consequently hampered.

Composition:
Each ml of injection contains 50 mg of tramadol hydrochloride.

Indications:
Effective for the treatment of acute and chronic pain are severe, including post-surgical pain, pain caused by diagnostic measures.

Dosage:
Oral therapy
Adults and children over 14 years.
Typical dosage:
single dose of 50 mg. The dose is usually sufficient to relieve pain, if it still feels the pain can be added to 50 mg after an interval of 30-60 minutes.

Maximum dose:
400 mg a day.

Doses are very dependent on the intensity of pain suffered.

Patients with impaired liver and kidney with creatinine clearance <30 ml / min:
50-100 mg every 12 hours, maximum 200 mg a day.

Parenteral Therapy
The dose administered should be adjusted to the intensity of pain. If no other instructions from the doctor, the dose given is as follows:

Adults or children over 14 years:
iv: 100 mg (1 ampule), slowly injected or dissolved in the infusion solution, and then infused.

i.m.: 100 mg (1 ampule)

subcutaneous: 100 mg (1 ampule)

The dose is usually sufficient to relieve pain. If you still feel pain, you can add 1 capsule tramadol 50 mg or 50 mg of tramadol injection (1 ml) after an interval of 30-60 minutes. In patients with impaired liver or renal function, dosage adjustments need to be done. The maximum dose of 400 mg / day.

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Alzheimer's drugs are Useful in the treatment of Heroin addiction

National University Hospital of Cheng Kung in Taiwan and the United States national institutes of health jointly develop a new treatment for heroin addiction based on a drug that is used to slow the progression of Alzheimer's disease.

Both these institutions have discovered, when every day consume less than five milligrams of Alzheimer's drugs, Ebixa (memantine), will be able to help heroin addicts use to reduce dependence on transitional therapy methadon methadon.

The drug is Methadon substitution of heroin and used to reduce the craving in heroin and any other actual opiates.

In clinical testing for three months by the hospital to the patient who is addicted to heroin, 90 found that 48 of them using the show a decreased reliance on Ebixa methadon, while 42 other patients who consumed a placebo became increasingly dependent on methadon.

In addition, Ebixa seem effective in protecting and regenerate nerves and noted that the researchers also noted the existence of a reduction in the number of neurotoxin (nerve poison) and such as perforin (cell poisons) in patients using the drug.

Transitional therapy, which started to use methadon in Taiwan since 2004, limited to eliminate drug addiction due to replace the sense of actual opiates anesthetic for a moment with actual opiates lasting, like methadon.

The hospital has taken a patent for the invention of memantine at play "protecting nerve degeneration caused by inflammation of the dopamine" in the United States and the European Union.

Dopamine nerve can be damaged by the use of the methadon, causing dependence on a substance, and Lu said that the discovery could help more people cured of addiction in the future if the new treatment was successfully promoted.

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