09 February 2014

Candesartan Drugs for Hypertension

Description:
Candesartan is a group of drugs called angiotensin II receptor antagonists. Candesartan keep blood vessels from narrowing, which reduces blood pressure and improve blood flow. Candesartan sometimes given in conjunction with other blood pressure medications.

Indications:
To treat high blood pressure (hypertension).

Dosage:

  1. The initial dose: 4 mg by mouth (orally), 1 times daily

  2. Increase dose with ambiguous times lipatkan dose until the highest dose that can be accepted patients, at a distance of more than 2 weeks.

  3. Target dose: 32 mg by mouth (orally), 1 times daily.

Side Effects:

  1. Usually settled and mild: CNS effects (dizziness); Effects of CV (orthostatic hypotension associated with dose, which may occur particularly in patients who lack the volume); kidney damage.

  2. Other effects are somewhat rare: rash, angioedema, raised LFTs (liver function tests); myalgia.

Special Instructions:

  1. Patients who lack the volume (eg high-dose diuretic therapy) may experience hypotension and should start with low doses.

  2. Use with caution in patients with renal artery stenosis, kidney damage or liver damage.

  3. Check your blood pressure (BP), renal function and electrolytes 1-2 weeks after the addition of each dose, at 3 months and then do every 6 months. (It takes more control in patients with previous or new experience renal dysfunction).

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