Pentoxifylline is a derivative of xanthine derivatives, facilitating the flow of blood. These drugs work by thinning the blood and increase the flexibility of red blood cells, causing blood to flow more easily through blood vessels.
Indications:
To treat intermittent klaudikasi (pain, cramping, numbness, weakness in the legs, hips, thighs and buttocks) in certain patients.
Dosage:
At first, 200 mg by mouth (orally), 3 times daily.
Maintenance dose: 100 mg by mouth (orally), 2-3 times daily, 200-300 mg intravenously through a vein (intra venous), repeat every 12 hours.
Maximum dose: 1200 mg / day
The release of the expanded: 400 mg by mouth (orally), 3 times a day and then
Maintenance dose: 400 mg by mouth (orally), 2-3 times a day
Side Effects:
CV effects (redness, sometimes cause arrhythmias, hypotension) GI effects (full gastric, N / V, diarrhea), dermatological effects (redden the skin, pruritus, urticaria); Reaction anaphylatic rare; CNS effects (sometimes cause dizziness, headache , agitation); effect of a rare hepatic (increased LFT), a rare haematological effects (bleeding, thrombocytopenia)
Special Instructions:
Contraindicated in patients with massive bleeding, extensive retinal hemorrhage.
Use with caution in patients with acute cardiac arrhythmias, MI, hypotension, impaired renal function, severe liver function impairment, increased risk of bleeding (eg treatment anticoagulant , anticoagulant disorders).
Indications:
To treat intermittent klaudikasi (pain, cramping, numbness, weakness in the legs, hips, thighs and buttocks) in certain patients.
Dosage:
At first, 200 mg by mouth (orally), 3 times daily.
Maintenance dose: 100 mg by mouth (orally), 2-3 times daily, 200-300 mg intravenously through a vein (intra venous), repeat every 12 hours.
Maximum dose: 1200 mg / day
The release of the expanded: 400 mg by mouth (orally), 3 times a day and then
Maintenance dose: 400 mg by mouth (orally), 2-3 times a day
Side Effects:
CV effects (redness, sometimes cause arrhythmias, hypotension) GI effects (full gastric, N / V, diarrhea), dermatological effects (redden the skin, pruritus, urticaria); Reaction anaphylatic rare; CNS effects (sometimes cause dizziness, headache , agitation); effect of a rare hepatic (increased LFT), a rare haematological effects (bleeding, thrombocytopenia)
Special Instructions:
Contraindicated in patients with massive bleeding, extensive retinal hemorrhage.
Use with caution in patients with acute cardiac arrhythmias, MI, hypotension, impaired renal function, severe liver function impairment, increased risk of bleeding (eg treatment anticoagulant , anticoagulant disorders).
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